Caring for Women,
One Early Diagnosis at a Time.
Key Statistics for Ovarian Cancer
Ovarian cancer is a leading cause of cancer deaths among women, accounting for more deaths than any other female reproductive system cancer. Nearly 20,000 new ovarian cancer cases are diagnosed in the U.S. each year, and for every 10 women diagnosed, 6 die of this disease annually.1
Key Facts:
- A woman's risk of ovarian cancer during her lifetime is about 1 in 87. Her lifetime chance of dying from ovarian cancer is less than 1% (not counting low malignant potential ovarian tumors.)1
- This cancer mainly occurs in women 63 years or older.1
- Less than 20% of ovarian cancers are found in the early stages before they spread beyond the ovary (most cases are identified at Stages 3-4).2
- The five-year survival rate for women with Stage I Epithelial Ovarian Cancer (EOC) is 93%, and it declines dramatically to 31% for those with advanced-stage tumors.3
Additional Information
There are several different subtypes of Epithelial Ovarian Cancer (EOC) including:
- Serous
- Endometroid
- Mucinous
- Clear Cell
HE4 complements CA 125 as an ovarian cancer marker. The combination of CA 125 and HE4 has higher sensitivity than either marker alone particularly in premenopausal women. HE4, together with CA 125 and menopausal status, make up the Risk of Malignancy Algorithm (ROMA) use to assess risk of ovarian cancer in patients with a pelvic mass, who are scheduled for surgery.
The ROMA score is used by Obstetricians and Gynecologists to appropriately triage patients, leading to improved patient care and decreased mortality.
Insights
Clinical Case Studies
Presented at the ACOG District XII 2022 Annual Meeting in Orlando
Clinical Case #1:
32-year-old premenopausal with pelvic pain
Dr. Richard Moore discusses this clinical case study at the ACOG District XII 2022 Annual District Meeting in Orlando.
Clinical Case #2:
46-year-old premenopausal with an adnexal mass
Dr. Richard Moore discusses this clinical case study at the ACOG District XII 2022 Annual District Meeting in Orlando.
Clinical Case #3:
72-year-old with BRCA-1 gene
Dr. Richard Moore discusses this clinical case study at the ACOG District XII 2022 Annual District Meeting in Orlando.
References
- American Cancer Society. (2024, January 19). Ovarian Cancer Statistics | How Common is Ovarian Cancer. www.cancer.org. https://www.cancer.org/cancer/types/ovarian-cancer/about/key-statistics…
- Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer Statistics, 2021. CA Cancer J Clin. 2021 Jan;71(1):7-33. doi: 10.3322/caac.21654. Epub 2021 Jan 12. Erratum in: CA Cancer J Clin. 2021 Jul;71(4):359. PMID: 33433946.
- Ovarian Cancer Survival Rates | Ovarian Cancer Prognosis | American Cancer Society